CHEMICAL STUDIES ON TOAD POISONS

[Safety measures in working with chemical poisons].

Studies on toad venom (3): effect of metals on the quality of toad venom torrefied on a metal plate.

To study the quality of toad venom dried on different metal plates by heating at 105 degrees C, each 20 g sample of fresh toad venom collected in Hei-Long-Jiang Province, China, was dried on (1) brass, (2) copper, (3) glass, (4) acrylic resins, (5) aluminum and (6) stainless-steel, respectively. Twelve bufadienolides, including bufalin and bufotalin, in each sample were then quantitatively anal...

Studies on the binding of aldosterone in the toad bladder.

The history of the chemical detection of poisons.

THE HISTORY OF THE CHEMICAL DETECTION OF POISONS In the seventeenth century even learned men believed in a bizarre folklore of poisoning, in which powdered emerald was a universal antidote and unicorn's horn an infallible detector of poison. When Richard Weston was tried in 1616 for the murder of Sir Thomas Overbury by means of arsenic and mercury, the jury was warned not to expect proof of the...

Chemical biology studies on norrisolide.

The cellular activity of norrisolide (7), a novel Golgi-vesiculating agent, was dissected as function of its chemical structure. This natural product induces irreversible vesiculation of the Golgi membranes and blocks protein transport at the level of the Golgi. The Golgi localization and fragmentation effects of 7 depend on the presence of the perhydroindane core, while the irreversibility of ...